| |
Species InformationThe Thermoplasma acidophilum DSM 1728 genome is 1.56 Million bp long and contains approximately 1530 predicted genes. T. acidophilum is a thermophilic, acidophilic mycoplasma that grows optimally at 59C and pH 2.0. This species is a facultative aerobe. The thermoplasamas are euryarchaea, distantly related to sulfolobes which are crenarchaea, yet both inhabit similar thermal acidic environments.
Taxonomy: Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; Thermoplasmataceae; Thermoplasma.
Sequencing: The sequence was released Sep 2000 by the Max Planck Institute, and was described in Nature 407:508-13 (2000) Ruepp A, Graml W, Santos-Martinez ML, Koretke KK, Volker C, et al.."The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum." Abstract: Thermoplasma acidophilum is a thermoacidophilic archaeon that thrives at 59 degrees C and pH 2, which was isolated from self-heating coal refuse piles and solfatara fields. Species of the genus Thermoplasma do not possess a rigid cell wall, but are only delimited by a plasma membrane. Many macromolecular assemblies from Thermoplasma, primarily proteases and chaperones, have been pivotal in elucidating the structure and function of their more complex eukaryotic homologues. Our interest... [Click above reference link for full abstract] Isolation: Science 170:1416-8 (1970) Darland G, Brock TD, Samsonoff W, Conti SF, "A thermophilic, acidophilic mycoplasma isolated from a coal refuse pile." Abstract: A thermophilic, acidophilic procaryote lacking a cell wall has been isolated from a coal refuse pile which had undergone self-heating. Electron micrographs, chemical assays for hexosamine, and the inability of vancomycin to inhibit growth confirm the lack of a cell wall. The apparent ability of the organism to reproduce by budding and the low guanine plus cytosine content of its DNA indicate a relation to the mycoplasmas. The temperature optimum of the organism is 59 degrees C, and... [Click above reference link for full abstract] Sequenced related species/strains: Ferroplasma acidarmanus Fer1, Picrophilus torridus DSM 9790, Thermoplasma volcanium GSS1 | Browse Specific Gene/Feature Sets |
|
Sample position queriesA genome position can be specified by chromosomal coordinate range, COGID, or keywords from the GenBank or TIGR description of a gene. The available chromosome/plasmid names are:
| Browser Chrom/Plasmid Name | Length (bp) | GC Content (%) | Gene Count | NCBI RefSeq Accession |
|---|
| chr | 1564906 | 45.99 | 1530 | NC_002578 |
The following list shows examples of valid position queries for thisgenome: | Request: | Genome Browser Response: |
|---|
| chr | Displays the entire sequence "chr" in the browser window | | chr:1-10000 | Displays first ten thousand bases of the sequence "chr" | | transporter | Lists all genes with "transporter" in the name or description | | Ta0008 | Display genome at position of gene Ta0008 |
Phylogenetic tree of related species based on multiple-genome alignment in browser:
CreditsThe Archaeal Genome Browsers at UCSC were developed by members of theLowe Lab (Kevin Schneider,Katherine Pollard, Andy Pohl, Todd Lowe) and Robert Baertsch, with significant support fromthe UCSC Human GenomeBrowser group.The Archaeal Browsers are run by a slightly modifiedversion of the UCSC Human GenomeBrowser system. All queries, bug reports, content corrections, suggested improvements,and new track data submissions should be sent to Todd Lowe (lowe@soe.ucsc.edu).If you use the browser in your published research, please cite ourpublication in the Nucleic Acids Research DatabaseIssue. Citations and positive feedback will help us obtain fundingto continue development of this community resource.
| |