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Species InformationThe Methanothermobacter thermautotrophicus str. Delta H genome is 1.75 Million bp long and contains approximately 1921 predicted genes. M. thermoautotrophicus is anaerobic and thermophilic. It grows at pH 7.2-7.6, and produces methane by reducing carbon dioxide.
Taxonomy: Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
Sequencing: The sequence was released Aug 1997 by the Oscient Pharmaceuticals Corporation, and was described in J Bacteriol 179:7135-55 (1997) Smith DR, Doucette-Stamm LA, Deloughery C, Lee H, Dubois J, et al.."Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics." Abstract: The complete 1,751,377-bp sequence of the genome of the thermophilic archaeon Methanobacterium thermoautotrophicum deltaH has been determined by a whole-genome shotgun sequencing approach. A total of 1,855 open reading frames (ORFs) have been identified that appear to encode polypeptides, 844 (46%) of which have been assigned putative functions based on their similarities to database sequences with assigned functions. A total of 514 (28%) of the ORF-encoded polypeptides are related to... [Click above reference link for full abstract] Isolation: J Bacteriol 109:707-15 (1972) Zeikus JG, Wolfe RS, "Methanobacterium thermoautotrophicus sp. n., an anaerobic, autotrophic, extreme thermophile." Abstract: The isolation of a new methanogenic bacterium, Methanobacterium thermoautotrophicus sp. n., is described. Successful isolation required a medium containing inorganic salts, an atmosphere consisting of an 80:20 mixture of hydrogen-carbon dioxide, and incubation temperatures of 65 to 70 C. Isolates of M. thermoautotrophicus were gram-positive, nonmotile, irregularly curved rods which frequently formed long filaments. The organism was found to be an autotroph and a strict anaerobe, and to... [Click above reference link for full abstract] Sequenced related species/strains: Methanobrevibacter smithii ATCC 35061, Methanosphaera stadtmanae DSM 3091 | Browse Specific Gene/Feature Sets |
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Sample position queriesA genome position can be specified by chromosomal coordinate range, COGID, or keywords from the GenBank or TIGR description of a gene. The available chromosome/plasmid names are:
| Browser Chrom/Plasmid Name | Length (bp) | GC Content (%) | Gene Count | NCBI RefSeq Accession |
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| chr | 1751377 | 49.54 | 1921 | NC_000916 |
The following list shows examples of valid position queries for thisgenome: | Request: | Genome Browser Response: |
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| chr | Displays the entire sequence "chr" in the browser window | | chr:1-10000 | Displays first ten thousand bases of the sequence "chr" | | transporter | Lists all genes with "transporter" in the name or description | | MTH10 | Display genome at position of gene MTH10 |
Phylogenetic tree of related species based on multiple-genome alignment in browser:
CreditsThe Archaeal Genome Browsers at UCSC were developed by members of theLowe Lab (Kevin Schneider,Katherine Pollard, Andy Pohl, Todd Lowe) and Robert Baertsch, with significant support fromthe UCSC Human GenomeBrowser group.The Archaeal Browsers are run by a slightly modifiedversion of the UCSC Human GenomeBrowser system. All queries, bug reports, content corrections, suggested improvements,and new track data submissions should be sent to Todd Lowe (lowe@soe.ucsc.edu).If you use the browser in your published research, please cite ourpublication in the Nucleic Acids Research DatabaseIssue. Citations and positive feedback will help us obtain fundingto continue development of this community resource.
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